Cognitive functioning in cannabis-using patients with schizophrenia. A comparative análisis

Vista sencilla de ítem
dc.contributor.affiliationUniversidad CES, Medellin, Colombia
dc.contributor.affiliationUniversidad Católica Luis Amigó, Medellin, Colombia
dc.contributor.affiliationCentro de atención en Neurología Pediátrica Integral (CENPI), Medellin, Colombia
dc.contributor.affiliationUniversidad de Medellín, Medellin, Colombia
dc.contributor.affiliationUniversidad de san Buenaventura, Bogota, Bogota, Colombia
dc.contributor.affiliationUniversidad Cardenal Herrera-CEU, Moncada, Spain
dc.contributor.affiliationHospital General Universitario de Valencia, Valencia, Spain
dc.contributor.authorL.A., Rojas Bernal, Luz Angela
dc.contributor.authorG.A., Castaño Pérez, Guillermo Alonso
dc.contributor.authornull
dc.contributor.authorL.C., Delgado, Liliana Claudia
dc.contributor.authorJ.M., Cuartas Arias, Jorge Mauricio
dc.contributor.authorA., Benito, A.
dc.date.accessioned2025-12-03T19:34:46Z
dc.date.available2025-12-03T19:34:46Z
dc.date.issued2025
dc.descriptionIntroduction. The growing evidence of cannabis (CN) use in patients with schizophrenia (SCZ) has increased interest in the study of the cognitive effects of CN in this population. Although some studies report superior cognitive functioning, other studies are contradictory. The objective was to compare cognitive functioning in CN users with SCZ (n=25), patients with SCZ without substance use (n=26) and healthy controls (n=25) between 18 and 35 years old. Method. Comparisons in sociodemographic and clinical variables and use characteristics were carried out using general linear models, Student's t and Chi squared test. Variables with significant differences were used to predict inclusion in the groups using multinomial and binary logistic regression. Neuropsychological tests and characteristics of CN consumption were correlated. Results. Although no differences in cognitive functioning were observed between groups with SCZ, the affected domains differed when compared to healthy controls. Age and results on different neuropsychological tests predicted inclusion in the SCZ+CN group. Significant correlations were found between the number of cannabis cigarettes (CN) consumed per week and the composite score of the perceptual reasoning index. Additionally, a significant relationship was observed between the CN abstinence period and performance on the Card Sorting subtest of the CCB within the BANFE. Conclusions. CN consumers with SCZ constitute a different subgroup of patients. Cannabis use characteristics correlate with scores from cognitive domains. Therefore, the approach must be differential. © 2025 Elsevier B.V., All rights reserved.
dc.identifier.doi10.21134/1001
dc.identifier.instnameinstname:Universidad de Medellínspa
dc.identifier.reponamereponame:Repositorio Institucional Universidad de Medellínspa
dc.identifier.repourlrepourl:https://repository.udem.edu.co/
dc.identifier.urihttp://hdl.handle.net/11407/9249
dc.language.isospa
dc.publisher.facultyInstituto de Ciencias Sociales y Humanasspa
dc.publisher.programPsicologíaspa
dc.relation.citationendpage47
dc.relation.citationissue2
dc.relation.citationstartpage28
dc.relation.citationvolume25
dc.relation.isversionofhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-105014813994&doi=10.21134%2F1001&partnerID=40&md5=709e8ff915617ebbb34f7e33fabb7808
dc.relation.referencesAlekseichuk, Ivan V., Spatial Working Memory in Humans Depends on Theta and High Gamma Synchronization in the Prefrontal Cortex, Current Biology, 26, 12, pp. 1513-1521, (2016)
dc.relation.referencesCuestionario De Identificacion De Los Transtornos Debidos Al Consumo De Alcohol, (2001)
dc.relation.referencesBarch, Deanna M., Cognition in schizophrenia: Core psychological and neural mechanisms, Trends in Cognitive Sciences, 16, 1, pp. 27-34, (2012)
dc.relation.referencesRosvold, Haldor Enger, A continuous performance test of brain damage, Journal of Consulting Psychology, 20, 5, pp. 343-350, (1956)
dc.relation.referencesBogaty, Sophia E.R., Meta-analysis of neurocognition in young psychosis patients with current cannabis use, Journal of Psychiatric Research, 99, pp. 22-32, (2018)
dc.relation.referencesBroyd, Samantha J., Acute and chronic effects of cannabinoids on human cognition - A systematic review, Biological Psychiatry, 79, 7, pp. 557-567, (2016)
dc.relation.referencesCoulston, Carissa M., The Neuropsychology of cannabis and other substance use in schizophrenia: Review of the literature and critical evaluation of methodological issues, Australian and New Zealand Journal of Psychiatry, 41, 11, pp. 869-884, (2007)
dc.relation.referencesDehais, Frédéric, Momentary lapse of control: A cognitive continuum approach to understanding and mitigating perseveration in human error, Neuroscience and Biobehavioral Reviews, 100, pp. 252-262, (2019)
dc.relation.referencesAdicciones, (2020)
dc.relation.referencesD'Souza, Deepak Cyril, Cannabis and psychosis/schizophrenia: Human studies, European Archives of Psychiatry and Clinical Neuroscience, 259, 7, pp. 413-431, (2009)
dc.rights.accesoRestricted access
dc.rights.accessrightsinfo:eu-repo/semantics/restrictedAccess
dc.sourceHealth and Addictions / Salud y Drogas
dc.sourceScopus
dc.subjectCannabis
dc.subjectCognition
dc.subjectDual Diagnosis
dc.subjectNeuropsychology
dc.subjectSchizophrenia
dc.titleCognitive functioning in cannabis-using patients with schizophrenia. A comparative análisis
dc.titleFuncionamiento cognitivo en pacientes consumidores de cannabis con esquizofrenia. Un análisis comparativo
dc.typeArticle
dc.type.localArtículospa
dc.type.versioninfo:eu-repo/semantics/publishedVersion

Archivos

Colecciones

Indexados Scopus